I had to go to Douglas, Arizona, to pick up a package. I could go several directions from there, one of which was north, up US-191. I've traveled several sections of that highway but not the entire thing. So why not?
US-191 would act like the spine of the trek, with various side trips along the way like ribs. No hurry. The traveling season is just starting. Give the northern latitudes time to warm up.
As ever, this plan is subject to change at any moment. I might get one of my sudden, overwhelming cravings for the ocean. Or weather might force me back. But wandering with a plan is better (maybe) than without one.